Severe head injury: the first hour.

Treatment for severe head injury.

Difficulties in establishing the value of certain treatments for head injury are reviewed. An analysis of 1000 severely head injured patients, managed by varying methods in three different countries, showed that certain treatments were more often used in the most severely injured patients. Even when the severity of injury was taken account of, it appeared that the use of steroids and tracheosto...

Patient after Severe Head Injury

Background: The pharmacodynamic differences in time to onset and dissipation of effect of sufentanil, fentanyl, and alfentanil probably result from different rates of blood-brain equilibration. The authors investigated this hypothesis in humans. Methods: After simultaneous central venous bolus application of sufentanil (10 pg), fentanyl (100 pg), and alfentanil (1,000 pg), arterial and jugular ...

Cognitive recovery after severe head injury

SYNOPSIS The Wechsler Adult Intelligence Scale (WAIS) was administered to two matched groups of severely head-injured patients. The first administration was early in the recovery period, when group I was still in post-traumatic amnesia. The WAIS results for this group were significantly lower than those of group II, who were fully conscious. A follow-up at a later stage of recovery found that g...

Outcome after severe non-accidental head injury.

Over the past three years 15 children have been admitted to the paediatric intensive care unit (PICU) at Addenbrooke's hospital suspected of having non-accidental injuries; presentation was diverse and often mild and out of proportion to the degree of morbidity seen at discharge and follow up. When compared with a group of similar aged children admitted to the PICU with severe head injury cause...

Neuroprotective agents in severe head injury.